Bioactivity-guided isolation of antimicrobial metabolite from Xylaria sp.
نویسندگان
چکیده
منابع مشابه
Effect of Culture Conditions on Metabolite Production of Xylaria sp.
Seeking a strategy for triggering the cryptic natural product biosynthesis to yield novel compounds in the plant-associated fungus Xylaria sp., the effect of culture conditions on metabolite production was investigated. A shift in the production of five known cytochalasin-type analogues 1-5 to six new α-pyrone derivatives, xylapyrones A-F (compounds 6-11), from a solid to a liquid medium was ob...
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CONTEXT The ethanol extracts and their fractions of three Indian medicinal plants, Ervatamia coronaria (Jacq.) Stapf, (Apocynaceae), Mimosa pudica L. (Mimosaceae) and Caesalpinia bonduc (L.) Roxb. (Caesalpiniaceae) were tested for their cytotoxic activity in the brine shrimp lethality (BSL) bioassay and in various cancer cell lines. The plants were selected based on their traditional use in the...
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In this study, antiproliferative activity of methanol extract of Centaura carduiformis DC. subsp. carduiformis var. carduiformis DC (CC) was examined against Vero, HeLa and C6 cell lines in 1000 and 500 mg/mL concentrations using the BrdU ELISA assay. The CC root (CCR) has the most effective antiproliferative activity. The root extract was fractionated using various solvent and determined antip...
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BACKGROUND Flowers of Bauhinia kockiana were investigated for their anticancer properties. METHODS Gallic acid (1), and methyl gallate (2), were isolated via bioassay-directed isolation, and they exhibited anticancer properties towards several cancer cell lines, examined using MTT cell viability assay. Pyrogallol (3) was examined against the same cancer cell lines to deduce the bioactive func...
متن کاملIsolation and structural elucidation of proline-containing cyclopentapeptides from an endolichenic Xylaria sp.
Two new cyclic pentapeptides (1 and 2) and the known blazein (3), ganodesterone (4), ergosterin (5), cerevisterol (6), 24-methylcholesta-4,6,8(14),22-tetraen-3-one (7), 5,8-epidioxyergosta-6,22-dien-3-ol (8), 16-α-d-mannopyranosyloxyisopimar-7-en-19-oic acid (9), and 16-hydroxy isopimar-7-en-19-oic acid (10) have been isolated from the crude extract of an endolichenic Xylaria sp. The structures...
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ژورنال
عنوان ژورنال: Process Biochemistry
سال: 2020
ISSN: 1359-5113
DOI: 10.1016/j.procbio.2020.01.028